Here's a neat transcript of a talk by Mat Marquis where he details how he made the Bocoup website lightning fast, particularly with snazzy font loading tricks and performance tools to help monitor those improvements over time.
Although, my favorite part of the talk is when Mat goes into why he wants to make websites:
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I don't get excited about frameworks or languages—I get excited about potential; about playing my part in building a more inclusive web.
I care about