Automatically back up your entire web server files and databases to Amazon S3
Christina Warren has a comprehensive and excellent tutorial on creating a Ruby script to back up your entire web server, including databases, and upload them directly to an Amazon S3 bucket. The tutorial is geared toward Media Temple, but I imagine could be adapted to other hosts. She also did a screencast demo demonstrating it all. This is high on my list of to-do's, and handy for me being on Media Temple and all.