This presentation by Miriam at DjangoCon US last summer is not only well done, but an insightful look at the current and future direction of CSS layout tools.
Many of us are familiar with Susy, the roll-your-own Grid system Miriam developed. We published a deep-dive on Susy a few years back to illustrate how easy it makes defining custom grid lines without the same pre-defined measures included in other CSS frameworks, like Foundation or Bootstrap. It really was (and is) a nice tool.
To watch Miriam give a talk that discourages using frameworks—even her very own—is a massive endorsement of more recent CSS developments, like Flexbox and Grid. Her talk feels even more relevant today than it was a few months ago in light of Eric Meyer's recent post on the declining complexity of CSS.
Yes, today's CSS toolkit feels more robust and the pace of development seems to have increased in recent years. But with it come new standards that replace the hacks we've grown accustomed to and, as a result, our beloved language becomes less complicated and less reliant on dependencies to make it do what we want.