I really have no idea how this will turn out. I suspect a ton of you have run or are currently running WordPress locally, but I have no clear guess on what the most popular way is to do that right now.
Let's limit the poll to how you are actually doing it, not how you wish you were doing it. And if you don't work with WordPress, but do work with a project that has similar dependencies (i.e. a server-side language, a database, and a web server), feel free to vote based on that project.