The first thing I would say is loose the Free quote sidebar thing. I have to say it’s gets annoying. Second thing is in FF 3.5 your navigation sidebar sort of breaks out the border. Actually I would say loose the sidebar all together as the one at the top is the same thing. For your typography I would use a sans-serif font like arial. For some reason your navigation looks "streteched out" kinda like you stretched horizontally. Also I would make your border on your portfolio more subtle use ligter colors, and drop the yellow border on your other images.
For SEO you need to give your site a name with the <title></title> tag other wise Google doesn’t have a name for it.