@teknofu, bro, i too have used underscores and it is pretty awesome. The html5 boilerplate make a html5 wordpress theme as well, but i have had a good amount of success with that. I say go for it! The more you mess around with stuff the more you learn (if you understand what it is you are doing). I say play around with the tutorial and give it a go, if it is to overwhelming then just use a reset theme as previously mentioned.