Adobe has put together some pretty compelling demos of “CSS Regions.” Download the package and run the included “Mini Browser” to see them. You define shapes (kinda like an image map) in which content flows. If needed, you define how the shapes are connected to one another and the order by which they do that. It’s a bit complicated and you’ll probably need some kind of GUI tool to help with the polygon code. It’s also a step forward in giving designers control to do amazing things on the web.